Aspirin is among those many drugs, which are used along with the insulin or without insulin, for the treatment of diabetes. This is because during this disease any other complications and illnesses develop which may have deadly consequences on the body and needed to be countered by different drug therapies. It is known that the aspirin causes little effect on the body of a diabetic but its actual upshot, and how it does this, is still fuzzy.
Aspirin therapy for diabetes
Thromboxane is a chemical substance which is produced in increased amounts in the body of a diabetic and it causes aggregation of the platelets in the blood, which causes blockage of the small blood vessels in the body. This is the fact that atherosclerosis and the vascular thrombosis are very common cardiovascular diseases in the diabetics and cause the death rate to be four times more than in those diabetics who do not have the cardiovascular diseases. To counter this lethal illness in the diabetics, aspirin therapies are used which acetylate the enzyme cyclo-oxygenage, which is responsible for the aggregation of the platelets.
For lowering the cardiovascular diseases in diabetics, a study suggests that therapy of 320 mg/day must be provided, of aspirin. Lower doses of aspirin may also be provided as secondary plan. Not only this, the aspirin also helps in preventing the onset of diabetic retinopathy. Though it is not yet recommended mode, aspirin therapy can be used as a primary and secondary preventive measure against the retinopathy.
To prevent the side effects of the medicine and make it to function more effectively, it is recommended to use lower dose of aspirin. Thromboxane synthesis is completely inhibited by administration of 70 mg of enteric-coated aspirin. This valuable effect of aspirin, which is extremely useful in those patients with less blood pressure than 160 mmHg, is responsible for 16% reduction in cardiovascular diseases and 68% reduction in myocardial infarction in the diabetes patients. This was disclosed after a study was carried out on a few thousands of diabetics.
Young diabetics are strongly discouraged from the use of aspirin because of the deadly side effects it has on the body, if used for a long time. Diabetics become vulnerable to the hemorrhagic stroke, and gastric mucosal injury. Bleeding starts from different parts of the body, including the intestinal walls. Problems of blood pressure and chronic renal diseases become more complex. Though it may prevent retinopathy but once the disease starts, aspirin cannot cure it or improve the situation.
